منابع مشابه
Antithyroid drug-induced agranulocytosis.
Antithyroid drugs are widely used to treat hyperthyroidism, especially Graves' disease, but they tend to cause agranulocytosis, which increases the mortality rate. Granulocyte colony-stimulating factor decreases the duration of recovery from agranulocytosis. We retrospectively studied cases of antithyroid drug-induced agranulocytosis over the past 10 years in a northern Taiwan medical center. A...
متن کاملAntithyroid drug-induced agranulocytosis.
Thyrotoxicosis is a common endocrine disorder. Antithyroid drug therapy is the standard treatment for this disease, especially in young women of reproductive age. A serious side effect of antithyroid drug use, however, is agranulocytosis. We report on two patients with antithyroid drug-induced agranulocytosis. Both patients presented with fever and severe neutropenia. The administration of gran...
متن کاملTherapeutic drug monitoring of antithyroid drugs in pregnancy: the knowledge gaps.
Despite being a common condition in pregnancy, and despite propylthiouracil (PTU) being perceived as safer than methimazole, there are virtually no epidemiological controlled studies on malformation rate an neurobehavioral outcomes with the former. This knowledge gap must be filled to ensure fetal safety.
متن کاملAntithyroid treatment: a personal series.
Introduction Since the introduction of thiouracil in 1943 antithyroid treatment for thyrotoxicosis has increased widely and has proved safer and more effective in carefully selected cases as the years have passed. Since 1951 carbimazole has been highly favoured in this country, being considered the least toxic agent in large-scale surveys (Burrell, Fraser & Doniach, 1956). Later (Willcox, 1962)...
متن کاملThe use of antithyroid drugs in pregnancy and lactation.
The management of hyperthyroidism in the pregnant woman has been the topic of several recent reviews (1–6) and case series (7–8). These papers have discussed maternal-fetal thyroid relationships, the epidemiology of maternal hyperthyroidism, causes of gestational thyrotoxicosis, the clinical and laboratory diagnosis of hyperthyroidism in pregnancy, therapy with ATDs, surgery, b adrenergic block...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 2012
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jc.2012-2123